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Aspirin production line-visual drug synthesis device
Summary: Serving the integration and intelligence of pharmaceutical, chemical, chemical, biological, food and other equipment, committed to the solution of the overall project plan, including the selection of project process supporting equipment, layout, automatic control supporting, engineering installation and construction, and cooperate with enterprises Carry out related system consultation and certification work.
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Aspirin production line (visualization)
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Key words:
Aspirin production line-visual drug synthesis device
Detailed introduction
All-glass visualization, both productive and instructive, not only meets the normal daily needs of the general laboratory, but also provides students with intuitive learning opportunities, and intelligence ensures the safety of the equipment.
To cultivate innovative consciousness and innovative ability, we take the comprehensive medicinal chemistry experiment "Synthesis of Aspirin, a century-old good drug" as an example to guide students to improve their scientific practice ability and stimulate interest in medicinal chemistry research by participating in the synthesis, separation and purification, product identification and other processes of drugs involved in the development and production of new drugs.
In this experiment, the preparation of aspirin, salicylic acid (o-hydroxybenzoic acid, molecular formula C7H603, molecular weight 138.12) as raw material, and acetic anhydride in the phenolic hydroxyl esterification reaction product, and the use of raw materials with phenolic hydroxyl indicator ferric chloride reagent color reaction, and the product does not react as an identification indicator. The salicylic acid used in the production can be obtained by hydrolysis of wintergreen oil (mainly containing methyl salicylate) extracted from the plant holly.
Core Features
Feature 1: The aspirin pilot synthesis device adopts 3D modeling and integrated design as a whole, optimizes the equipment layout, and occupies a small space. The reaction kettle, crystallization kettle, condenser, collection tank and high-level tank are made of high borosilicate glass material, which has good chemical and physical properties and good process visibility;
Feature 2: valves and instruments are pneumatic/solenoid valves and explosion-proof temperature and pressure transmitters, supporting PLC control system, can achieve isolated operation and remote monitoring.
Feature 3: supporting the overall anti-splash leakage device to ensure the effective collection of material leakage, pipeline disassembly, cleaning and other liquids, to prevent the liquid from flowing into the laboratory floor, and to meet EHS requirements; Custom walk-in fume hood and exhaust gas collection and processing device can be selected to realize non-contact experimental operation and meet EHS requirements.
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